Open AccessImpact of higher hemoglobin targets on blood pressure and clinical outcomes: a secondary analysis of CHOIR
Author(s) -
Jula K. Inrig,
Shelly Sapp,
Huiman X. Barnhart,
Uptal D. Patel,
Donal Reddan,
Ajay Singh,
Robert M. Califf,
Lynda A. Szczech
Publication year - 2012
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfs123
Subject(s) - medicine , hemoglobin , blood pressure , kidney disease , adverse effect , intensive care medicine , cardiology
Targeting a higher hemoglobin in patients with chronic kidney disease leads to adverse cardiovascular outcomes, yet the reasons remain unclear. Herein, we sought to determine whether changes in erythropoiesis-stimulating agent (ESA) dose and in hemoglobin were predictive of changes in blood pressure (BP) and whether these changes were associated with cardiovascular outcomes.
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