Osteoprotegerin as a predictor of renal and cardiovascular outcomes in renal transplant recipients: follow-up data from the ALERT study | Zendy

My Svensson | Zendy; Dag Olav Dahle | Zendy; Geir Mjøen | Zendy; Gisela Weihrauch | Zendy; Hubert Scharnagl | Zendy; Harald Dobnig | Zendy; Winfried März | Zendy; Alan G. Jardine | Zendy; Bengt Fellström | Zendy; Hallvard Holdaas | Zendy

Open Access

Osteoprotegerin as a predictor of renal and cardiovascular outcomes in renal transplant recipients: follow-up data from the ALERT study

Author(s) -

My Svensson,

Dag Olav Dahle,

Geir Mjøen,

Gisela Weihrauch,

Hubert Scharnagl,

Harald Dobnig,

Winfried März,

Alan G. Jardine,

Bengt Fellström,

Hallvard Holdaas

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr694

Subject(s) - medicine , hazard ratio , renal function , osteoprotegerin , transplantation , creatinine , kidney disease , kidney transplantation , cohort , gastroenterology , proportional hazards model , urology , cardiology , confidence interval , receptor , activator (genetics)

In patients with chronic kidney disease, vascular calcification contributes to increased cardiovascular (CV) morbidity and mortality. CV risk remains high after successful renal transplantation. Osteoprotegerin (OPG) is a glycoprotein, involved in the regulation of the vascular calcification process. Previous studies have shown that elevated OPG is predictive of mortality in high-risk populations. The aim of this study was to investigate the prognostic value of OPG for graft function, CV events and all-cause death, in a large transplant cohort.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research