Open AccessThe German Chronic Kidney Disease (GCKD) study: design and methods
Author(s) -
KaiUwe Eckardt,
Barbara Bärthlein,
Seema BaidAgrawal,
Andreas Beck,
Martin Busch,
Frank Eitner,
Arif B. Ekici,
Jürgen Floege,
Olaf Gefeller,
Herman Haller,
R. Hilge,
Karl F. Hilgers,
Jan T. Kielstein,
Vera Krane,
Anna Köttgen,
Florian Kronenberg,
Peter J. Oefner,
HansUlrich Prokosch,
André Reis,
Matthias Schmid,
Elke Schäeffner,
Ulla T. Schultheiß,
Susanne A. Seuchter,
Thomas Sitter,
Claudia Sommerer,
Gerd Walz,
C. Wanner,
Günter Wolf,
Martin Zeier,
Stephanie Titze
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr456
Subject(s) - medicine , kidney disease , nephrology , renal replacement therapy , renal function , observational study , proteinuria , intensive care medicine , cohort study , prospective cohort study , cohort , disease , kidney
Chronic kidney disease (CKD) is increasingly recognized as a global health problem. The conditions leading to CKD, the health impact of CKD and the prognosis differ markedly between affected individuals. In particular, renal failure and cardiovascular mortality are competing risks for CKD patients. Opportunities for targeted intervention are very limited so far and require an improved understanding of the natural course of CKD, of the risk factors associated with various clinical end points and co-morbidities as well as of the underlying pathogenic mechanisms.
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