Open Access4-Hydroxy-2-hexenal-induced apoptosis in human renal proximal tubular epithelial cells
Author(s) -
Eun Hui Bae,
SiHyun Cho,
So Young Joo,
Сарсенова Л.К.,
S. H. Kim,
J. Lee,
Soo Wan Kim
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr386
Subject(s) - medicine , apoptosis , microbiology and biotechnology , cancer research , pathology , biochemistry , chemistry , biology
The aldehyde products of lipid peroxidation such as 4-hydroxy-2-hexenal (HHE) might be responsible for the pathogenesis of kidney injury. The present study was aimed to investigate the effects of HHE on renal tubular epithelial cells and its signaling mechanisms.
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