Effects of concomitant hepatitis C virus infection in patients with underlying lupus nephritis on long-term renal outcome
Author(s) -
A H Mitwalli,
Ashik Hayat,
Jamal Al-Wakeel,
D Durdana Hammad
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr327
Subject(s) - medicine , lupus nephritis , concomitant , kidney disease , hepatitis c , hepatitis c virus , transplantation , end stage renal disease , hemodialysis , gastroenterology , disease , immunology , virus
Despite recent advances in the management of lupus nephritis (LN), these unfortunate patients are at a higher risk of developing chronic kidney disease (CKD). Concomitant chronic hepatitis C virus (HCV) infection is associated with adverse outcome in patients with LN and further compounds the risk as some of these patients choose to undergo kidney transplantation in the near future. Objectives. The aim of the present study is to evaluate the long-term impact of chronic HCV infection in patients with underlying Class IV LN on renal function, progression to end-stage renal disease (ESRD) and patient survival.
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