Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension | Zendy

Anna Steć | Zendy; Andrzej Semczuk | Zendy; Jacek Furmaga | Zendy; Andrzej Książek | Zendy; Monika Buraczyńska | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension

Author(s) -

Anna Steć,

Andrzej Semczuk,

Jacek Furmaga,

Andrzej Książek,

Monika Buraczyńska

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr293

Subject(s) - medicine , end stage renal disease , genotype , gastroenterology , odds ratio , allele , kidney disease , hemodialysis , endocrinology , genetics , gene , biology

Renalase is a novel flavin adenine dinucleotide-dependent amine oxidase that is secreted by the kidney. It circulates in the blood and modulates the cardiac function and systemic blood pressure. Insufficiency of renalase in patients with chronic kidney disease may explain the frequent occurrence of hypertension among patients with end-stage renal disease (ESRD) and an increased risk of cardiovascular events in this group. The aim of the study was to assess the relationship of two renalase gene polymorphisms with hypertension in dialysed patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research