Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells | Zendy

Barry D. Hock | Zendy; K. A. Mackenzie | Zendy; Nicholas B. Cross | Zendy; K. G. Taylor | Zendy; Margaret J. Currie | Zendy; Bridget A. Robinson | Zendy; Jeremy Simcock | Zendy; Judith L. McKenzie | Zendy

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Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells

Author(s) -

Barry D. Hock,

K. A. Mackenzie,

Nicholas B. Cross,

K. G. Taylor,

Margaret J. Currie,

Bridget A. Robinson,

Jeremy Simcock,

Judith L. McKenzie

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr264

Subject(s) - medicine , cd14 , flow cytometry , kidney disease , myeloid derived suppressor cell , gastroenterology , immunosurveillance , immunology , cancer , suppressor

Cancer, particularly cutaneous squamous cell carcinoma (SCC), is a major cause of mortality in renal transplant recipients (RTRs). Myeloid-derived suppressor cells (MDSC) play a central role in suppressing cancer immunosurveillance but their potential mobilisation in RTRs and levels relative to those of other immunoregulatory dendritic cell (DC) populations have not been analysed.

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