Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice | Zendy

Igor Nikolov | Zendy; Nobuhiko Joki | Zendy; Thao NguyenKhoa | Zendy; Ida Chiara Guerrera | Zendy; Julien Maizel | Zendy; Joyce Benchitrit | Zendy; Luciene M. dos Reis | Zendy; Aleksander Edelman | Zendy; Bernard Lacour | Zendy; Vanda Jorgetti | Zendy; Tilman B. Drüeke | Zendy; Ziad A. Massy | Zendy

Open Access

Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice

Author(s) -

Igor Nikolov,

Nobuhiko Joki,

Thao NguyenKhoa,

Ida Chiara Guerrera,

Julien Maizel,

Joyce Benchitrit,

Luciene M. dos Reis,

Aleksander Edelman,

Bernard Lacour,

Vanda Jorgetti,

Tilman B. Drüeke,

Ziad A. Massy

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr254

Subject(s) - sevelamer , phosphate binder , medicine , endocrinology , calcification , lanthanum carbonate , apolipoprotein e , kidney disease , hyperphosphatemia , disease

Atherosclerosis and vascular calcification (VC) progression in chronic kidney disease is favored by disturbances of mineral metabolism. We compared the effect of phosphate binder lanthanum (La) carbonate with sevelamer-HCl on atherosclerosis, VC and bone structure and function in mice with chronic renal failure (CRF).

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