Lupus nephritis: prolonged immunoadsorption (IAS) reduces proteinuria and stabilizes global disease activity
Author(s) -
Georg Stummvoll,
Sabine Schmaldienst,
Josef S Smolen,
Kurt Derfler,
Peter Biesenbach
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr239
Subject(s) - medicine , proteinuria , immunoadsorption , lupus nephritis , gastroenterology , systemic lupus erythematosus , adverse effect , autoantibody , nephritis , anti dsdna antibodies , extracorporeal , disease , immunology , kidney , antibody
Systemic lupus erythematosus (SLE) is characterized by pathogenic autoantibodies, which can be removed by extracorporeal procedures. While previous studies have shown short-term efficacy of immunoadsorption (IAS) in SLE, no information on long-term benefit and safety is available.
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