Pathology of idiopathic nephrotic syndrome in children: are the adolescents different from young children? | Zendy

Muhammed Mubarak | Zendy; Javed Iqbal Kazi | Zendy; Ali Asghar Lanewala | Zendy; S. Hashmi | Zendy; Faheem Akhter | Zendy

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Pathology of idiopathic nephrotic syndrome in children: are the adolescents different from young children?

Author(s) -

Muhammed Mubarak,

Javed Iqbal Kazi,

Ali Asghar Lanewala,

S. Hashmi,

Faheem Akhter

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr221

Subject(s) - medicine , nephrotic syndrome , pathological , focal segmental glomerulosclerosis , minimal change disease , idiopathic nephrotic syndrome , membranoproliferative glomerulonephritis , pediatrics , age of onset , young adult , glomerulonephritis , pathology , disease , kidney , proteinuria

There is no specific data on the pathological lesions underlying idiopathic nephrotic syndrome (INS) in adolescents in Pakistan. Moreover, it is not known whether the pathological lesions in adolescents differ significantly from young children with INS in our setup. Materials and methods. A retrospective analysis was carried out on all patients with INS with onset ≤ 18 years of age. They were split into two groups: patients with onset of INS ≤ 12 years (young children group) and patients with onset ≥ 13 through 18 years of age (adolescent group). Renal biopsies were evaluated by light microscopy, immunoflourescence and electron microscopy. The histopathological lesions on renal biopsies were analyzed and compared between the two groups.

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