Online high-efficiency haemodiafiltration achieves higher serum free light chain removal than high-flux haemodialysis in multiple myeloma patients: preliminary quantitative study
Author(s) -
A. Granger Vallee,
Leïla Chénine,
Hélène LerayMoragues,
Laure Patrier,
Chantal Cognot,
Guillaume Cartron,
JeanPaul Cristol,
Bernard Canaud
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr180
Subject(s) - medicine , multiple myeloma , urology , hemodialysis , ultrafiltration (renal) , immunoglobulin light chain , chromatography , renal replacement therapy , gastroenterology , antibody , chemistry , immunology
Fast reduction of serum free light chain (FLC) levels correlate with renal recovery in cast nephropathy. Because convection has the capacity to remove proteins of higher molecular weights, we hypothesized that haemodiafiltration (HDF) would be superior to haemodialysis (HD) for FLC clearance.
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