Immune complexes in acute adult-onset Henoch-Schonlein nephritis
Author(s) -
Marc Hilhorst,
Pieter van Paassen,
P. van Breda Vriesman,
Jan Willem Cohen Tervaert
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfr149
Subject(s) - medicine , nephritis , nephropathy , immune system , glomerulonephritis , pathology , immunology , immune complex disease , purpura (gastropod) , disease , kidney disease , immune complex , kidney , biology , endocrinology , ecology , diabetes mellitus
Adult-onset Henoch-Schönlein purpura nephritis (HSPN) and primary IgA (IgAN) nephropathy have been considered indistinguishable immunohistopathologically and are often considered as two extremes of one disease entity. We postulate that adult-onset Henoch-Schönlein can be distinguished histologically from primary IgAN and that both diseases differ in their immunopathological mechanisms.
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