Aminoglycoside-induced nephrotoxicity studied by proton magnetic resonance spectroscopy of urine | Zendy

V. Tzovaras | Zendy; Vasilis Tsimihodimos | Zendy; Christina Kostara | Zendy; Zoi Mitrogianni | Zendy; Moses Elisaf | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Aminoglycoside-induced nephrotoxicity studied by proton magnetic resonance spectroscopy of urine

Author(s) -

V. Tzovaras,

Vasilis Tsimihodimos,

Christina Kostara,

Zoi Mitrogianni,

Moses Elisaf

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr074

Subject(s) - aminoglycoside , medicine , nephrotoxicity , antibiotics , urine , gastroenterology , gentamicin , amikacin , urology , kidney , pharmacology , endocrinology , microbiology and biotechnology , biology

Acute kidney injury is a relatively common complication of aminoglycoside therapy that affects 10-20% of patients receiving antibiotics of this class. Although the vast majority of patients do recover, the presence of certain risk factors may alter the clinical presentation and result in permanent renal damage. Thus, aminoglycoside-induced nephrotoxicity is a major concern and early diagnosis is critical. The aim of the present study was to characterize the early stages of aminoglycoside-induced nephrotoxicity using proton nuclear magnetic resonance ((1)H NMR) spectroscopy of urine.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research