Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy | Zendy

J. M. Cruzado | Zendy; Rafael Poveda | Zendy; Meritxell Ibernón | Zendy; Mario Díaz | Zendy; Xavier Fulladosa | Zendy; M. Carrera | Zendy; Josep Torras | Zendy; Oriol Bestard | Zendy; I. Navarro | Zendy; José Ballarín | Zendy; R. Romero | Zendy; J. M. Grinyó | Zendy

Open Access

Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy

Author(s) -

J. M. Cruzado,

Rafael Poveda,

Meritxell Ibernón,

Mario Díaz,

Xavier Fulladosa,

M. Carrera,

Josep Torras,

Oriol Bestard,

I. Navarro,

José Ballarín,

R. Romero,

J. M. Grinyó

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr072

Subject(s) - medicine , urology , renal function , sirolimus , enalapril , proteinuria , nephropathy , atorvastatin , glomerulosclerosis , kidney disease , endocrinology , gastroenterology , kidney , angiotensin converting enzyme , blood pressure , diabetes mellitus

There is a lack of new therapeutic strategies for IgA nephropathy. Low-dose sirolimus inhibits mesangial cell proliferation and renal fibrosis in animal models.

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