CD4+CD28null cells are expanded and exhibit a cytolytic profile in end-stage renal disease patients on peritoneal dialysis | Zendy

Ashok Kumar Yadav | Zendy; Vivekanand Jha | Zendy

Open Access

CD4+CD28null cells are expanded and exhibit a cytolytic profile in end-stage renal disease patients on peritoneal dialysis

Author(s) -

Ashok Kumar Yadav,

Vivekanand Jha

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr010

Subject(s) - medicine , cd28 , granzyme b , perforin , peritoneal dialysis , granzyme a , population , immunology , cd8 , granzyme , end stage renal disease , t cell , endocrinology , gastroenterology , hemodialysis , immune system , environmental health

End-stage renal failure patients, including those on peritoneal dialysis (PD), exhibit several nontraditional cardiovascular (CV) risk factors. A role of CD4(+)CD28(null) T lymphocytes in the genesis of coronary artery disease (CAD) has been proposed. We investigated this cell population and examined its phenotype in a cohort of PD patients without CV disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research