Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate | Zendy

Henrik Reinhard | Zendy; Peter Riis Hansen | Zendy; Frederik Persson | Zendy; Lise Tarnow | Zendy; Niels Wiinberg | Zendy; Andreas Kjær | Zendy; Cecilie Petersen | Zendy; K. Winther | Zendy; H.H. Parving | Zendy; Peter Rossing | Zendy; Peter Karl Jacobsen | Zendy

Open Access

Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate

Author(s) -

Henrik Reinhard,

Peter Riis Hansen,

Frederik Persson,

Lise Tarnow,

Niels Wiinberg,

Andreas Kjær,

Cecilie Petersen,

K. Winther,

H.H. Parving,

Peter Rossing,

Peter Karl Jacobsen

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfr009

Subject(s) - medicine , asymptomatic , coronary artery disease , cardiology , excretion , endocrinology

Elevated plasma N-terminal (NT)-proBNP levels and coronary calcium score (CCS) not only predicts myocardial ischaemia and coronary artery stenosis but also adverse cardiovascular events and mortality in type 2 diabetic patients with an increased urinary albumin excretion rate (UAER), whereas low levels are associated with low frequency of coronary artery disease (CAD) and good prognosis. The underlying causes of poor prognosis in patients with elevated NT-proBNP are not known; thus, we investigated the role of putative asymptomatic CAD in type 2 diabetic patients with UAER >30 mg/24 h and elevated P-NT-proBNP and/or CCS.

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