Outcome of idiopathic membranous nephropathy using targeted stepwise immunosuppressive treatment strategy | Zendy

Sari Aaltonen | Zendy; Eero Honkanen | Zendy

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Outcome of idiopathic membranous nephropathy using targeted stepwise immunosuppressive treatment strategy

Author(s) -

Sari Aaltonen,

Eero Honkanen

Publication year - 2011

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfq841

Subject(s) - medicine , membranous nephropathy , retrospective cohort study , renal function , surgery , kidney disease , renal replacement therapy , proteinuria , gastroenterology , kidney

The natural course of idiopathic membranous nephropathy (IMN) is variable and the role of immunosuppressive therapy is controversial. In our centre, the strategy has been conservative: the immunomodulating treatment (glucocorticoids and/or cyclosporine A) has been targeted to patients at high risk of developing progressive renal disease and the cytotoxic drugs have been used cautiously. The aim of this retrospective observational study was to evaluate the efficacy of this strategy.

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