Are ACEI/ARBs associated with the decreased peritoneal protein clearance in long-term PD patients?
Author(s) -
Min Zhuo,
Jinpei Dong,
Yingdong Zheng,
Luo Zuo
Publication year - 2011
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq764
Subject(s) - medicine , peritoneal dialysis , proportional hazards model , confounding , population , diabetes mellitus , cohort , urology , endocrinology , environmental health
Objective. Peritoneal protein clearance (PrC) is recognized as a new marker of systemic endothelial dysfunction and predictor of mortality in patients on peritoneal dialysis (PD). Given that angiotensin-converting enzyme inhibitors (ACEI)/angiotensin II receptor blockers (ARBs) could improve endothelial dysfunction in the general population, we aim to explore whether this benefit is present in the PD population.
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