Effectiveness of cinacalcet in patients with recurrent/persistent secondary hyperparathyroidism following parathyroidectomy: results of the ECHO study | Zendy

Emanuel Zitt | Zendy; Rix M | Zendy; Pablo Torres | Zendy; Denis Fouque | Zendy; Stefan H. Jacobson | Zendy; Frank Pétavy | Zendy; Bastian Dehmel | Zendy; Monika RybaStanisławowska | Zendy

Open Access

Effectiveness of cinacalcet in patients with recurrent/persistent secondary hyperparathyroidism following parathyroidectomy: results of the ECHO study

Author(s) -

Emanuel Zitt,

Rix M,

Pablo Torres,

Denis Fouque,

Stefan H. Jacobson,

Frank Pétavy,

Bastian Dehmel,

Monika RybaStanisławowska

Publication year - 2010

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfq641

Subject(s) - cinacalcet , medicine , secondary hyperparathyroidism , parathyroidectomy , urology , calcimimetic , hyperparathyroidism , vitamin d and neurology , parathyroid hormone , gastroenterology , surgery , endocrinology , calcium

Progressive secondary hyperparathyroidism (sHPT) is characterized by parathyroid gland hyperplasia which may ultimately require parathyroidectomy (PTX). Although PTX is generally a successful treatment for those patients subjected to surgery, a significant proportion develops recurrent sHPT following PTX. ECHO was a pan-European observational study which evaluated the achievement of KDOQI(TM) treatment targets with cinacalcet use in patients on dialysis. Previously published results showed that cinacalcet plus flexible vitamin D therapy lowered serum PTH, phosphorus and calcium in the clinical practice with similar efficacy as seen in phase III trials.

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