Dialysis modality-dependent changes in serum metabolites: accumulation of inosine and hypoxanthine in patients on haemodialysis | Zendy

JiYoung Choi | Zendy; Young-Zoon Yoon | Zendy; H.-J. Choi | Zendy; So Hyun Park | Zendy; C.-D. Kim | Zendy; I.-S. Kim | Zendy; TaeHwan Kwon | Zendy; J.-Y. Do | Zendy; Sunghoon Kim | Zendy; Do Hyun Ryu | Zendy; GeumSook Hwang | Zendy; Y.-L. Kim | Zendy

Open Access

Dialysis modality-dependent changes in serum metabolites: accumulation of inosine and hypoxanthine in patients on haemodialysis

Author(s) -

JiYoung Choi,

Young-Zoon Yoon,

H.-J. Choi,

So Hyun Park,

C.-D. Kim,

I.-S. Kim,

TaeHwan Kwon,

J.-Y. Do,

Sunghoon Kim,

Do Hyun Ryu,

GeumSook Hwang,

Y.-L. Kim

Publication year - 2010

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfq554

Subject(s) - medicine , hypoxanthine , inosine , dialysis , hemodialysis , modality (human–computer interaction) , intensive care medicine , biochemistry , adenosine , enzyme , chemistry , human–computer interaction , computer science

The body metabolism of patients with end-stage renal disease may be altered in response to long-term dialysis treatment. Moreover, the pattern of serum metabolites could change depending on the type of dialysis modality used. However, dialysis modality-dependent changes in serum metabolites are poorly understood. Our aim was to profile comprehensively serum metabolites by exploiting a novel method of (1)H-NMR-based metabonomics and identify the differences in metabolite patterns in subjects receiving haemodialysis (HD) and peritoneal dialysis (PD).

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