High prevalence of renal dysfunction in children after liver transplantation: non-invasive diagnosis using a cystatin C-based equation | Zendy

Florian Brinkert | Zendy; Marius Kemper | Zendy; Andrea BriemRichter | Zendy; Martin Husen | Zendy; András Treszl | Zendy; Rainer Ganschow | Zendy

Open Access

High prevalence of renal dysfunction in children after liver transplantation: non-invasive diagnosis using a cystatin C-based equation

Author(s) -

Florian Brinkert,

Marius Kemper,

Andrea BriemRichter,

Martin Husen,

András Treszl,

Rainer Ganschow

Publication year - 2010

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfq548

Subject(s) - medicine , cystatin c , liver transplantation , transplantation , liver dysfunction , hepatic dysfunction , gastroenterology , intensive care medicine , creatinine

Chronic kidney disease (CKD) has been increasingly shown to be a negative prognostic factor after liver transplantation (Ltx). Creatinine-based glomerular filtration rate (GFR) formulas are notoriously insensitive. In children, non-invasive determination of GFR by measurement of serum cystatin C is feasible and repeatedly correlated to the gold standards of GFR measurements. The aim of our study was to determine GFR using cystatin C (GFR(cys)) in comparison with conventional calculated creatinine clearance (GFR(crea)) in the long-term follow-up after paediatric liver transplantation (pLtx) in a large number of patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research