Role of HIV-1 DNA levels as clinical marker of HIV-1-associated nephropathies
Author(s) -
Hassane Izzedine,
V. Acharya,
Marc Wirden,
P Cluzeł,
D. Sène,
Gregory M. Lucas,
A Baumelou,
Mohamed G. Atta
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq414
Subject(s) - peripheral blood mononuclear cell , nephropathy , medicine , viral load , immunology , virology , population , rna , renal biopsy , biopsy , virus , pathology , biology , gene , endocrinology , diabetes mellitus , environmental health , biochemistry , in vitro
HIV-associated nephropathy (HIVAN) is usually diagnosed in virologically uncontrolled infected patients. However, HIVAN can occur in some cases with undetectable HIV-1 RNA levels. We suggested that intracellular HIV-1 proviral DNA load can be used as a marker in this particular patient population.
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