Open AccessAutocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans
Author(s) -
Bernd Hohenstein,
Moore Dr Colin,
C. Foellmer,
Kerstin Amann,
Rolf A. Brekken,
Christoph Daniel,
C. P. M. Hugo
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq200
Subject(s) - medicine , vegf receptors , autocrine signalling , glomerulonephritis , vascular endothelial growth factor , endocrinology , cancer research , kidney , receptor
Vascular endothelial growth factor (VEGF) is the most important and tightly regulated angiogenic cytokine in the kidney. Its activity is critical for capillary/glomerular preservation and repair, and recent studies have also demonstrated its relevance for the preservation of podocytes.
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