Open AccessProtein-enriched diet increases water absorption via the aquaporin-2 water channels in healthy humans
Author(s) -
Thomas Guldager Lauridsen,
Henrik Vase,
Jørn Starklint,
Jesper Nørgaard Bech,
E. B. Pedersen
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq111
Subject(s) - endocrinology , medicine , epithelial sodium channel , vasopressin , sodium , aquaporin 2 , excretion , hypertonic saline , kidney , aldosterone , reabsorption , chemistry , mechanical engineering , organic chemistry , water channel , engineering , inlet
According to animal experiments, a protein-enriched diet increased renal absorption of sodium and water. We wanted to test the hypothesis that a protein-enriched diet would increase the expression of the aquaporin-2 water channels and the epithelial sodium channels in the distal part of the nephron using biomarkers for the activity of the two channels.
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