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Long-term control of parathyroid hormone and calcium-phosphate metabolism after parathyroidectomy in children with chronic kidney disease
Author(s) -
Betti Schaefer,
Katja Schlosser,
Elke Wühl,
P. Schall,
Günter Klaus,
Franz Schaefer,
Claus Peter Schmitt
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq074
Subject(s) - medicine , parathyroidectomy , secondary hyperparathyroidism , kidney disease , parathyroid hormone , autotransplantation , hyperparathyroidism , endocrinology , transplantation , urology , bone remodeling , parathyroid gland , dialysis , gastroenterology , refractory (planetary science) , kidney transplantation , surgery , calcium , physics , astrobiology
Hyperparathyroidism (HPT) is an essential contributor to bone disease and cardiovascular calcifications in children with chronic kidney disease (CKD). Pharmacological and dietary interventions are of limited efficacy; calcimimetics are not yet recommended in children. Parathyroidectomy (PTX) is ultimately performed if HPT becomes refractory to conservative measures; the long-term results and the impact of subsequent kidney transplantation (NTX), however, have not yet been evaluated.

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