A comparison of nephron number, glomerular volume and kidney weight in Senegalese Africans and African Americans | Zendy

Bridgette McNamara | Zendy; Boucar Diouf | Zendy; R. N. Douglas-Denton | Zendy; Michael D. Hughson | Zendy; Wendy E. Hoy | Zendy; John F. Bertram | Zendy

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A comparison of nephron number, glomerular volume and kidney weight in Senegalese Africans and African Americans

Author(s) -

Bridgette McNamara,

Boucar Diouf,

R. N. Douglas-Denton,

Michael D. Hughson,

Wendy E. Hoy,

John F. Bertram

Publication year - 2010

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfq030

Subject(s) - nephron , medicine , kidney , renal function , endocrinology , kidney disease , urology

Low nephron number is determined in utero and is a proposed risk for essential hypertension. Glomerular volume is inversely correlated with nephron number, and genetic and environmental factors that determine nephron number are thought to determine glomerular volume. This study compared total glomerular (nephron) number (N(glom)), mean glomerular volume (V(glom)) and kidney weight in two geographically separated black populations with significant common genetic ancestry.

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