Peritonitis-free survival in peritoneal dialysis: an update taking competing risks into account
Author(s) -
David W. Evans,
J.-P. Ryckelynck,
Emmanuel Fabre,
Christian Verger
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfq003
Subject(s) - medicine , peritoneal dialysis , peritonitis , survival analysis , log rank test , proportional hazards model , cohort , incidence (geometry) , surgery , optics , physics
Peritonitis-free survival is commonly reported in the peritoneal dialysis (PD) literature. The Kaplan-Meier method appears to be the only technique used to date, although it has known limitations for cohorts with multiple outcomes, as in PD. In the presence of these 'competing risks' outcomes, the Kaplan-Meier estimate is interpretable only under restrictive assumptions. In contrast, methods which take competing risks into account provide unbiased estimates of probabilities of outcomes as actually experienced by patients.
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