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Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease
Author(s) -
Elizabeth C. Lorenz,
Sanjeev Sethi,
Tanya L. Poshusta,
Marina Ramı́rez-Alvarado,
Shaji Kumar,
Donna J. Lager,
Fernando C. Fervenza,
Nelson Leung
Publication year - 2010
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfp735
Subject(s) - medicine , amyloidosis , al amyloidosis , immunoglobulin light chain , nephropathy , multiple myeloma , kidney disease , pathology , endocrinology , immunology , diabetes mellitus , antibody
Renal dysfunction commonly occurs in multiple myeloma (MM) and is caused by deposition of abnormal light chain within various compartments of the kidney. Renal pathologic findings are diverse and include cast nephropathy (CN), amyloidosis and light-chain deposition disease (LCDD). We report a case of renal failure in a patient with MM caused by concurrent CN, amyloidosis and LCDD which has not been previously described.

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