An unusual case of hyponatraemia
Author(s) -
J. Jacobi,
Sören Schnellhardt,
Anke Kulschewski,
Kerstin Amann,
Michael A. Kuefner,
KaiUwe Eckardt,
K. F. Hilgers
Publication year - 2009
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfp698
Subject(s) - medicine , adrenal insufficiency , primary adrenal insufficiency , addison's disease , hyponatremia , pathophysiology , differential diagnosis , intensive care medicine , disease , adrenal disorder , pediatrics , diabetes mellitus , endocrinology , pathology , insulin resistance , glucose homeostasis
The differential diagnosis of hyponatraemia is manifold and includes hormonal disorders such as primary adrenal insufficiency or hypothyroidism. The diagnosis of adrenal insufficiency is always suggestive in cases of hypotension associated with hyponatraemia, hyperkalaemia and metabolic acidosis. We herein report a case of severe hyponatraemia in a patient with Addison's disease. The underlying cause was disseminated adrenal tuberculosis without any evidence of other organ involvement. To date, tuberculosis remains a frequent cause of adrenal insufficiency although the pathophysiology of adrenal tropism is poorly understood.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom