Reduction of biofilm formation with trisodium citrate in haemodialysis catheters: a randomized controlled trial | Zendy

Jan Bosma | Zendy; C. E. H. Siegert | Zendy; P. G. H. Peerbooms | Zendy; Marcel C. Weijmer | Zendy

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Reduction of biofilm formation with trisodium citrate in haemodialysis catheters: a randomized controlled trial

Author(s) -

Jan Bosma,

C. E. H. Siegert,

P. G. H. Peerbooms,

Marcel C. Weijmer

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp651

Subject(s) - medicine , trisodium citrate , randomized controlled trial , reduction (mathematics) , hemodialysis , surgery , urology , biochemistry , chemistry , geometry , mathematics

Formation of an intraluminal microbial biofilm is noted to play a significant role in the development of catheter-related infections (CRIs). Recently, it has been demonstrated that trisodium citrate (TSC) has superior antimicrobial effects over heparin for catheter locking. In this randomized controlled trial, we compared the influence of catheter locking with heparin and TSC on the in vivo intraluminal biofilm formation in haemodialysis catheters.

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