Calcitonin-stimulated renal Ca2+ reabsorption occurs independently of TRPV5
Author(s) -
Yu-Yu Hsu,
Henrik Dimke,
Joost G.J. Hoenderop,
R.J.M. Bindels
Publication year - 2009
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfp645
Subject(s) - medicine , reabsorption , calcitonin , transient receptor potential channel , endocrinology , renal physiology , calcitonin receptor , kidney , receptor , calcitonin gene related peptide , neuropeptide
Calcitonin (CT) is known to affect renal Ca(2+) handling. However, it remains unclear how CT affects Ca(2+) transport in the distal convolutions. The aim of this study was to investigate the contribution of the renal epithelial Ca(2+) channel, transient receptor potential vanilloid 5 (TRPV5), to renal Ca(2+) handling in response to CT.
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