Free p-cresylsulphate is a predictor of mortality in patients at different stages of chronic kidney disease | Zendy

Sophie Liabeuf | Zendy; Daniela Veit Barreto | Zendy; Fellype Carvalho Barreto | Zendy; Natalie Meert | Zendy; Griet Glorieux | Zendy; Eva Schepers | Zendy; M. Temmar | Zendy; Gabriel Choukroun | Zendy; Raymond Vanholder | Zendy; Ziad A. Massy | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Free p-cresylsulphate is a predictor of mortality in patients at different stages of chronic kidney disease

Author(s) -

Sophie Liabeuf,

Daniela Veit Barreto,

Fellype Carvalho Barreto,

Natalie Meert,

Griet Glorieux,

Eva Schepers,

M. Temmar,

Gabriel Choukroun,

Raymond Vanholder,

Ziad A. Massy

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp592

Subject(s) - medicine , kidney disease , cohort , hemodialysis , arterial stiffness , renal function , calcification , gastroenterology , endocrinology , blood pressure

Uraemic toxins are considered to be emerging mortality risk factors in chronic kidney disease (CKD) patients. p-Cresol (a prototype protein-bound uraemic retention solute) has been shown to exert toxic effects in vitro. Recently, it has been demonstrated that p-cresol is present in plasma as its sulphate conjugate, p-cresylsulphate. The present study evaluated the distribution of free and total p-cresylsulphate and sought to determine whether these parameters were associated with vascular calcification, arterial stiffness and mortality risk in a cohort of CKD patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research