Altering peritoneal membrane function: removing the GAG? | Zendy

Donald Fraser | Zendy; Nicholas Topley | Zendy

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Altering peritoneal membrane function: removing the GAG?

Author(s) -

Donald Fraser,

Nicholas Topley

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp440

Subject(s) - peritoneal dialysis , mesothelial cell , peritoneal cavity , medicine , membrane , mesothelium , ultrafiltration (renal) , extracellular matrix , peritoneum , biophysics , microbiology and biotechnology , pathology , anatomy , biochemistry , chemistry , biology

Peritoneal dialysis (PD) is a highly effective and convenient mode of renal replacement therapy. The success of PD de- pends on maintaining the structural and functional integrity of the peritoneal membrane. The outer (serosal) part of the peritoneal membrane consists of a monolayer of mesothe- lial cells, which provide a low-friction surface, allowing internal organs to move relative to one another. The mem- brane acts as a selective permeability barrier, regulating the passageofwaterandsolutesbetweentheintravascularcom-

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