FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese | Zendy

Shufeng Zhou | Zendy; Ji-Cheng Lv | Zendy; Lei Yu | Zendy; Zhao Cui | Zendy; Juan Zhao | Zendy; Rui Yang | Zendy; J. Han | Zendy; Ping Hou | Zendy; MingHui Zhao | Zendy; Hengguo Zhang | Zendy

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FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese

Author(s) -

Shufeng Zhou,

Ji-Cheng Lv,

Lei Yu,

Zhao Cui,

Juan Zhao,

Rui Yang,

J. Han,

Ping Hou,

MingHui Zhao,

Hengguo Zhang

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp374

Subject(s) - genotyping , genotype , haplotype , allele , medicine , genetics , polymorphism (computer science) , taqman , immunology , gene , biology , polymerase chain reaction

The Fcgamma receptors play important roles in anti-glomerular basement membrane antibody disease (anti-GBM disease) in animal models, and FCGR gene polymorphisms have been reported to be associated with numerous human autoimmune diseases. We aimed to clarify the genetic association of FCGR gene polymorphisms with anti-GBM disease in Chinese patients.

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