Increased renoprotection with ACE inhibitor plus aldosterone antagonist as compared to monotherapies—the effect on podocytes | Zendy

Zalán Németh | Zendy; Gábor Kökény | Zendy; Mária Godó | Zendy; Miklós Mózes | Zendy; László Rosivall | Zendy; Marie-Luise Groß | Zendy; Eberhard Ritz | Zendy; Péter Hamar | Zendy

Open Access

Increased renoprotection with ACE inhibitor plus aldosterone antagonist as compared to monotherapies—the effect on podocytes

Author(s) -

Zalán Németh,

Gábor Kökény,

Mária Godó,

Miklós Mózes,

László Rosivall,

Marie-Luise Groß,

Eberhard Ritz,

Péter Hamar

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp371

Subject(s) - medicine , aldosterone , antagonist , pharmacology , urology , endocrinology , receptor

Blockade of the renin-angiotensin-aldosterone system (RAAS) does not completely prevent progression of renal disease. Mineralocorticoid receptor blockade provides additional renoprotection over ACE-inhibition monotherapy. We examined the mechanisms underlying superior renoprotection in the subtotal nephrectomy (SNX) model.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research