Open AccessOsmomediated natriuresis in humans: the role of vasopressin and tubular calcium sensing
Author(s) -
Ewout J. Hoorn,
M. Carola Zillikens,
H. A. P. Pols,
A.H. Jan Danser,
Frans Boomsma,
Robert Zietse
Publication year - 2009
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfp303
Subject(s) - natriuresis , endocrinology , vasopressin , medicine , hypertonic saline , arginine vasopressin receptor 2 , kidney , receptor , antagonist
The aim was to investigate the unknown mechanism of osmomediated natriuresis. This is the phenomenon by which hypertonic saline (HS) produces a larger natriuresis than isotonic saline (IS), despite the same sodium content.
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