The impact of arteriovenous fistulas on aortic stiffness in patients with chronic kidney disease | Zendy

M. S. Utescu | Zendy; A. Leboeuf | Zendy; Nadia Chbinou | Zendy; Simon Desmeules | Zendy; Marcel Lebel | Zendy; Mohsen Agharazii | Zendy

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The impact of arteriovenous fistulas on aortic stiffness in patients with chronic kidney disease

Author(s) -

M. S. Utescu,

A. Leboeuf,

Nadia Chbinou,

Simon Desmeules,

Marcel Lebel,

Mohsen Agharazii

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp276

Subject(s) - medicine , arterial stiffness , cardiology , pulse wave velocity , pulse pressure , hemodynamics , blood pressure , kidney disease , diastole , end stage renal disease , hemodialysis

The creation of arteriovenous fistulas (AVF) in patients with advanced chronic kidney disease (CKD) has been shown to have adverse effects on their central pulse wave profile suggesting a likely increase in arterial stiffness. The aim of the present study was to directly evaluate the effect of AVF on arterial stiffness. Method. Thirty-one stage-5 CKD patients underwent haemodynamic assessment prior to and 3 months after creation of AVF. Haemodynamic assessment included measurement of blood pressure (BP), central and carotidal pulse wave profile analysis, and carotido-femoral and carotido-radial pulse wave velocities (PWV). Pre-AVF and post-AVF haemodynamic parameters were compared using the Wilcoxon signed-rank test or the paired Student t-test as appropriate. Pearson correlations, single and multiple linear regressions, were used to determine the association between variables.

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