Pre-kidney-transplant blood transfusions do not improve transplantation outcome: a Dutch national study
Author(s) -
Jeroen Aalten,
F. J. Bemelman,
E.M. Van Den BergLoonen,
Frans H.J. Claas,
Maarten H. L. Christiaans,
Johan W. de Fijter,
Bouke G. Hepkema,
R. J. Hené,
J.J. Homan van der Heide,
J. P. van Hooff,
Neubury M. Lardy,
S P Lems,
H.G. Otten,
W Weimar,
Wil A. Allebes,
Andries J. Hoitsma
Publication year - 2009
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfp233
Subject(s) - medicine , sensitization , transplantation , human leukocyte antigen , complement dependent cytotoxicity , kidney transplantation , blood transfusion , immunology , antibody , antigen , monoclonal antibody , antibody dependent cell mediated cytotoxicity
Female renal transplant candidates are prone to be sensitized by prior pregnancies, and undetected historical sensitization might decrease transplantation outcome. Hypothesis of our study was that pre-transplant blood transfusions (PTFs) can elucidate historical sensitization and that the avoidance of the associated antigens can improve transplantation outcome.
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