Serum proteome alteration of severe sepsis in the treatment of continuous renal replacement therapy | Zendy

Yu Gong | Zendy; Nan Chen | Zendy; Fuqiang Wang | Zendy; Zhaohui Wang | Zendy; Huaxi Xu | Zendy

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Serum proteome alteration of severe sepsis in the treatment of continuous renal replacement therapy

Author(s) -

Yu Gong,

Nan Chen,

Fuqiang Wang,

Zhaohui Wang,

Huaxi Xu

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp231

Subject(s) - proteome , sepsis , renal replacement therapy , proteomics , medicine , western blot , peptide mass fingerprinting , intensive care , two dimensional gel electrophoresis , gel electrophoresis , blood proteins , bioinformatics , biochemistry , biology , intensive care medicine , gene

Continuous renal replacement therapy (CRRT) techniques have occupied an important position in the intensive care units (ICU). Serum proteome alteration and protein removal in this process are not clear. Since it has a poor understanding of mechanism of the treatment, there is a specific need of proteomics research for CRRT. The aim of this research was to study the serum proteome alterations of severe sepsis patients in the treatment of CRRT. Improved knowledge of proteome alteration could lead to the development of more efficient treatment strategies.

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