A population-based assessment of the familial component of acute kidney allograft rejection
Author(s) -
Alexander S. GoldfarbRumyantzev,
Fuad S. Shihab,
Lyska L. Emerson,
Geri Mineau,
Carla Schaefer,
Hongying Tang,
Cheri Hunter,
Natalie Naiman,
L. Smith,
Richard A. Kerber
Publication year - 2009
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfp086
Subject(s) - medicine , population , kidney transplantation , retrospective cohort study , kidney transplant , component (thermodynamics) , kidney , intensive care medicine , environmental health , physics , thermodynamics
The genetic determinants of acute kidney transplant rejection (AR) are not well studied, and familial aggregation has never been demonstrated. The goal of this retrospective case-control study was to exploit the unique nature of the Utah Population Database (UPDB) to evaluate if AR or rejection-free survival aggregates in families.
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