Monocytes/macrophages in kidney allograft intimal arteritis: no association with markers of humoral rejection or with inferior outcome | Zendy

Nicolas Kozakowski | Zendy; Georg A. Böhmig | Zendy; Markus Exner | Zendy; A. Soleiman | Zendy; Nicole Huttary | Zendy; Katalin Nagy-Bojarszky | Zendy; Rupert Ecker | Zendy; Željko Kikić | Zendy; Heinz Regele | Zendy

Open Access

Monocytes/macrophages in kidney allograft intimal arteritis: no association with markers of humoral rejection or with inferior outcome

Author(s) -

Nicolas Kozakowski,

Georg A. Böhmig,

Markus Exner,

A. Soleiman,

Nicole Huttary,

Katalin Nagy-Bojarszky,

Rupert Ecker,

Željko Kikić,

Heinz Regele

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp045

Subject(s) - medicine , arteritis , humoral immunity , immune system , pathology , kidney , immunology , kidney transplantation , graft rejection , antibody , transplantation

Several studies indicate that interstitial and intracapillary monocytes/macrophages (MO) represent a significant proportion of graft-infiltrating cells in renal allografts and that their presence may unfavourably affect clinical outcome. Much less is known about the role of MO in vascular rejection of transplanted kidneys. The aim of our study was to determine the cellular composition of immune cell infiltrates in intimal arteritis and to analyse whether it is associated with features of humoral immunity and impaired graft survival.

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