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Available data indicate that serum phosphate increases only when glomerular filtration rate (GFR) falls into the low range (&lt;60 mL/min x 1.73 m(2)). GFR and serum phosphate decrease with ageing. This population-based study investigated by age-controlled analyses the relationship of GFR with serum phosphate in adults with GFR above the low range.

Glomerular filtration rate and serum phosphate: an inverse relationship diluted by age