Proteomic analysis of urine from proteinuric patients shows a proteolitic activity directed against albumin | Zendy

Riccardo Magistroni | Zendy; Giulia Ligabue | Zendy; Valentina Lupo | Zendy; Luciana Furci | Zendy; Marco Leonelli | Zendy; Luca Manganelli | Zendy; Mario Masellis | Zendy; Valentina Gatti | Zendy; Fabrizio Cavazzini | Zendy; Walter Tizzanini | Zendy; A Albertazzi | Zendy

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Proteomic analysis of urine from proteinuric patients shows a proteolitic activity directed against albumin

Author(s) -

Riccardo Magistroni,

Giulia Ligabue,

Valentina Lupo,

Luciana Furci,

Marco Leonelli,

Luca Manganelli,

Mario Masellis,

Valentina Gatti,

Fabrizio Cavazzini,

Walter Tizzanini,

A Albertazzi

Publication year - 2009

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfp020

Subject(s) - albumin , medicine , nephrotic syndrome , proteinuria , urine , chromatography , urinary system , proteolytic enzymes , trichloroacetic acid , biochemistry , chemistry , kidney , enzyme

Nephrotic syndrome is a condition that is clinically associated with poor outcome. In this study, we compared different techniques of urine sample preparation in order to develop a robust analytical protocol to define the differential urinary proteome of urinary abnormalities compared to nephrotic proteinuria.

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