Reduced progression of adriamycin nephropathy in spontaneously hypertensive rats treated by losartan
Author(s) -
Nevena MihailovicStanojevic,
Djurdjica Jovović,
Zoran Miloradović,
Jelica Grujić-Milanović,
Mirjana Jerkić,
Jasmina MarkovicLipkovski
Publication year - 2008
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfn596
Subject(s) - losartan , medicine , hypertensive nephropathy , nephropathy , endocrinology , hypertensive disease , urology , angiotensin receptor , angiotensin ii , pharmacology , kidney , receptor , diabetic nephropathy , blood pressure , diabetes mellitus
The aim of the study was to investigate the antihypertensive effects of angiotensin II type-1 receptor blocker, losartan, and its potential in slowing down renal disease progression in spontaneously hypertensive rats (SHR) with adriamycin (ADR) nephropathy.
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