AA amyloidosis due to chronic oxalate arthritis and vasculitis in a patient with secondary oxalosis after jejunoileal bypass surgery | Zendy

T. Cornelis | Zendy; Bert Bammens | Zendy; E. Lerut | Zendy; L Cosyn | Zendy; G. Goovaerts | Zendy; R Westhovens | Zendy; Yves Vanrenterghem | Zendy

Open Access

AA amyloidosis due to chronic oxalate arthritis and vasculitis in a patient with secondary oxalosis after jejunoileal bypass surgery

Author(s) -

T. Cornelis,

Bert Bammens,

E. Lerut,

L Cosyn,

G. Goovaerts,

R Westhovens,

Yves Vanrenterghem

Publication year - 2008

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfn392

Subject(s) - medicine , vasculitis , amyloidosis , jejunoileal bypass , dialysis , aa amyloidosis , surgery , hemodialysis , arthritis , gastroenterology , disease , obesity , weight loss , morbid obesity , familial mediterranean fever

We report a case of a woman with secondary oxalosis after jejunoileal bypass surgery for obesity, who presented with oxalate stone disease and renal insufficiency requiring dialysis. Thirty years after surgery, longstanding osteoarticular symptoms were recognized as oxalate arthritis. Eventually, she also developed oxalate vasculitis, which improved with corticoid treatment and intensification of dialysis. Work-up for kidney transplantation revealed AA amyloidosis on gastric and colonic biopsies. Since no other cause of chronic inflammation could be identified, it was concluded that the amyloidosis was secondary to oxalate arthritis and vasculitis. To our knowledge, this is the first report on this association.

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