Calcium load during administration of calcium carbonate or sevelamer in individuals with normal renal function | Zendy

T. Heinrich | Zendy; H. Heidt | Zendy; Verena Häfner | Zendy; H. Schmidt-Gayk | Zendy; Ekkehart Jenetzky | Zendy; I. WalterSack | Zendy; Gerd Mikus | Zendy; J. Bommer | Zendy

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Calcium load during administration of calcium carbonate or sevelamer in individuals with normal renal function

Author(s) -

T. Heinrich,

H. Heidt,

Verena Häfner,

H. Schmidt-Gayk,

Ekkehart Jenetzky,

I. WalterSack,

Gerd Mikus,

J. Bommer

Publication year - 2008

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfn151

Subject(s) - sevelamer , medicine , calcium , endocrinology , excretion , placebo , crossover study , urinary calcium , urinary system , urine , phosphate binder , hyperphosphatemia , pathology , alternative medicine

Under steady-state conditions urinary calcium (Ca) excretion corresponds to the Ca load in healthy subjects. However, in chronic haemodialysis patients reliable data on Ca load are not available. In these patients Ca-containing phosphate binders are suspected to play a role in the progression of arteriosclerosis via increased but not quantified Ca load. The present study evaluated the effect of calcium carbonate (CC) and sevelamer hydrochloride (SEV), a calcium-free phosphate binder, on serum Ca and urinary Ca excretion in healthy individuals.

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