Inflammatory markers and the progression of IgA glomerulonephritis
Author(s) -
Kati Kaartinen,
Jaana Syrjänen,
Ilkka Pörsti,
Mikko Hurme,
Aimo Harmoinen,
Amos Pasternack,
Heini Huhtala,
Jukka Mustonen
Publication year - 2007
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfm782
Subject(s) - medicine , gastroenterology , creatinine , renal function , proteinuria , dialysis , white blood cell , kidney disease , cystatin c , immunology , kidney
IgA glomerulonephritis (IgAGN) composes a variable prognosis with 15-40% of the patients eventually progressing to end-stage renal failure. Known risk factors for progressive course of IgAGN include hypertension, proteinuria and renal insufficiency. Although markers of inflammation such as serum or urinary interleukin-6 (IL-6) and serum albumin have predicted progression in some studies, sensitive CRP (hs-CRP) has not been directly linked to the progression of IgAGN.
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