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Type 2 diabetes is associated with a high cardiovascular risk, which is even increased if renal damage is superimposed. Peripheral blood mononuclear cells (PBMCs) and pro-inflammatory cytokines are key factors linking type 2 diabetes and atherosclerosis. We investigated the influence of renal damage on serum, urinary and PBMCs expression behavior of TNF-alpha and IL-6 in these patients.

nephrology, dialysis, transplantation/nephrology dialysis transplantation

Influence of renal involvement on peripheral blood mononuclear cell expression behaviour of tumour necrosis factor- and interleukin-6 in type 2 diabetic patients