Open AccessA Comparison of GFR estimating formulae based upon s-cystatin C and s-creatinine and a combination of the two
Author(s) -
M. Tidman,
Per Sjöström,
Ian L. Jones
Publication year - 2007
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfm661
Subject(s) - cystatin c , renal function , creatinine , urology , medicine , iohexol , cystatin , kidney disease
Current recommendations (KDIGO and NKF-K/DOQI) are that patients with chronic kidney diseases (CKD) should be classified in stages 1-5 based on GFR. A serum creatinine-based prediction equation (abbreviated MDRD formula) can be used to estimate GFR (eGFR). Cystatin C has been proposed as an alternative filtration marker to creatinine. We present validation of currently used formulae for eGFR based upon s-creatinine and s-cystatin C and we compare two different methods for the determination of cystatin C.
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