Chemical reactions of vitamin C with intravenous-iron formulations | Zendy

Shuang Wang | Zendy; Giuseppe Geraci | Zendy; Martin K. Kuhlmann | Zendy; Nathan W. Levin | Zendy; Garry J. Handelman | Zendy

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Chemical reactions of vitamin C with intravenous-iron formulations

Author(s) -

Shuang Wang,

Giuseppe Geraci,

Martin K. Kuhlmann,

Nathan W. Levin,

Garry J. Handelman

Publication year - 2007

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfm557

Subject(s) - vitamin , vitamin c , chemistry , reagent , whole blood , medicine , chromatography , biochemistry , organic chemistry

Intravenous (IV) iron is widely prescribed for patients on haemodialysis, to replace iron losses during treatment. It releases labile iron, which can induce oxidation of vitamin C and trigger oxidant damage. We examined the stability of vitamin C in the presence of IV iron compounds. We further examined in the ability of vitamin C to release iron from these compounds.

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